Trains run fairly constantly between London and Manchester, with fares being dependent upon your time of travel. Virgins trains do have Wi-Fi available and the ride is fairly quick.
Sample Trip From Manchester Piccadilly to London Euston
Depart: 4:35pm BST, MANCHESTER PICCADILLY
Arrive: 6:48pm BST, LONDON EUSTON
Booking Rate: £ 29.00
An off-peak return ticket can be up to approximately £ 72.00